Association of a Polymorphism of BTN2A1 With Hypertension in Japanese Individuals
Author(s) -
Hideki Horibe,
K. Kato,
Mitsutoshi Oguri,
Tetsuro Yoshida,
Tetsuo Fujimaki,
Toshiki Kawamiya,
Kiyoshi Yokoi,
Shingo Watanabe,
K. Satoh,
Yukitoshi Aoyagi,
Masato Tanaka,
Hideyo Yoshida,
Shoji Shinkai,
Y Nozawa,
Toyoaki Murohara,
Yoko Yamada
Publication year - 2011
Publication title -
american journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.009
H-Index - 136
eISSN - 1941-7225
pISSN - 0895-7061
DOI - 10.1038/ajh.2011.74
Subject(s) - medicine , odds ratio , blood pressure , genotype , risk factor , essential hypertension , allele , myocardial infarction , logistic regression , polymorphism (computer science) , cardiology , genetics , gene , biology
We previously showed that the C→T polymorphism (rs6929846) in butyrophilin, subfamily 2, member A1 gene (BTN2A1) was associated with myocardial infarction in Japanese individuals. Given that hypertension is a major risk factor for myocardial infarction, the association of rs6929846 of BTN2A1 with myocardial infarction might be attributable, at least in part, to its effect on susceptibility to hypertension. We have thus examined the relation of rs6929846 of BTN2A1 to hypertension in Japanese individuals.
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