Impaired Endothelium Independent Vasodilation in Nonobstructive Hypertrophic Cardiomyopathy | Zendy

Francesco Bartolomucci | Zendy; M. D. Michele | Zendy; M. Kozakovà | Zendy; Federica Cipriani | Zendy; F. Polemio | Zendy; Carlo Palombo | Zendy

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Impaired Endothelium Independent Vasodilation in Nonobstructive Hypertrophic Cardiomyopathy

Author(s) -

Francesco Bartolomucci,

M. D. Michele,

M. Kozakovà,

Federica Cipriani,

F. Polemio,

Carlo Palombo

Publication year - 2011

Publication title -

american journal of hypertension

Language(s) - Uncategorized

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1038/ajh.2011.66

Subject(s) - medicine , cardiology , brachial artery , vasodilation , hypertrophic cardiomyopathy , muscle hypertrophy , left ventricular hypertrophy , blood pressure

In patients with hypertrophic cardiomyopathy (HCM) an impaired microvascular function is reported not only in the hypertrophied septum but also in the nonhypertrophied left ventricular free wall as well as in forearm resistance vessels, thus suggesting a generalized alteration in vascular function. However, information on conduit artery involvement is still sparse and controversial. The aim of this study was to evaluate whether functional abnormalities are detectable in the arteries of HCM patients.

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