Methionine-Induced Homocysteinemia Impairs Endothelial Function in Hypertensives: The Role of Asymmetrical Dimethylarginine and Antioxidant Vitamins | Zendy

D. Tousoulis | Zendy; George Bouras | Zendy; Charalambos Antoniades | Zendy; K. Marinou | Zendy; Νικόλαος Παπαγεωργίου | Zendy; Antigoni Miliou | Zendy; Georgios Hatzis | Zendy; Elli Stefanadi | Zendy; Costas Tsioufis | Zendy; Christodoulos Stefanadis | Zendy

Open Access

Methionine-Induced Homocysteinemia Impairs Endothelial Function in Hypertensives: The Role of Asymmetrical Dimethylarginine and Antioxidant Vitamins

Author(s) -

D. Tousoulis,

George Bouras,

Charalambos Antoniades,

K. Marinou,

Νικόλαος Παπαγεωργίου,

Antigoni Miliou,

Georgios Hatzis,

Elli Stefanadi,

Costas Tsioufis,

Christodoulos Stefanadis

Publication year - 2011

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1038/ajh.2011.65

Subject(s) - asymmetric dimethylarginine , endothelial dysfunction , homocysteine , medicine , endocrinology , methionine , placebo , endothelium , nitric oxide , hyperhomocysteinemia , arginine , biochemistry , chemistry , amino acid , alternative medicine , pathology

Nitric oxide synthase (NOS) inhibitor asymmetrical dimethylarginine (ADMA) is synthesized by the methylation of arginine as part of the methionine/homocysteine cycle. However, the mechanisms regulating ADMA synthesis in hypertension are unclear.

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