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The present study examined the inhibitory action of temporary treatment with an angiotensin type 1 (AT(1)) receptor blocker (ARB) on vascular remodeling using hypertensive mice with overexpression of the human renin (hRN) and angiotensinogen (hANG) genes.

Temporary Treatment With AT1 Receptor Blocker, Valsartan, From Early Stage of Hypertension Prevented Vascular Remodeling