Temporary Treatment With AT1 Receptor Blocker, Valsartan, From Early Stage of Hypertension Prevented Vascular Remodeling | Zendy

Shinji Inaba | Zendy; Masaru Iwai | Zendy; Megumi Furuno | Zendy; Harumi Kanno | Zendy; Izumi Senba | Zendy; Hideki Okayama | Zendy; Masaki Mogi | Zendy; Jitsuo Higaki | Zendy; Masatsugu Horiuchi | Zendy

Open Access

Temporary Treatment With AT1 Receptor Blocker, Valsartan, From Early Stage of Hypertension Prevented Vascular Remodeling

Author(s) -

Shinji Inaba,

Masaru Iwai,

Megumi Furuno,

Harumi Kanno,

Izumi Senba,

Hideki Okayama,

Masaki Mogi,

Jitsuo Higaki,

Masatsugu Horiuchi

Publication year - 2011

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1038/ajh.2011.6

Subject(s) - valsartan , medicine , hydralazine , endocrinology , angiotensin ii receptor type 1 , angiotensin receptor , oxidative stress , renin–angiotensin system , blood pressure , angiotensin ii , vascular smooth muscle , pharmacology , smooth muscle

The present study examined the inhibitory action of temporary treatment with an angiotensin type 1 (AT(1)) receptor blocker (ARB) on vascular remodeling using hypertensive mice with overexpression of the human renin (hRN) and angiotensinogen (hANG) genes.

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