Open AccessCCR5 deficiency does not reduce hypertensive end-organ damage in mice
Author(s) -
Christian F. Krebs,
Christoph Fraune,
Robin Schmidt-Haupt,
JanEric Turner,
Ulf Panzer,
Michael Nguyen Quang,
Andrea Tannapfel,
Joachim Velden,
Rolf A.K. Stahl,
Ulrich Wenzel
Publication year - 2012
Publication title -
american journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.009
H-Index - 136
eISSN - 1941-7225
pISSN - 0895-7061
DOI - 10.1038/ajh.2011.243
Subject(s) - medicine , endocrinology , kidney , blood pressure , receptor , chemokine , fibrosis , angiotensin ii , albuminuria , chemokine receptor
CCR5 is expressed on infiltrating T cells in hypertensive mice and CCR5 antagonists reduce hypertension making CCR5 an interesting target in treatment of hypertension.
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