Novel Genetic Variation in Exon 28 of FBN1 Gene Is Associated With Essential Hypertension | Zendy

Chong Shen | Zendy; Xiangfeng Lu | Zendy; Laiyuan Wang | Zendy; Shufeng Chen | Zendy; Yun Li | Zendy; Xiaoli Liu | Zendy; Jianxin Li | Zendy; Jianfeng Huang | Zendy; Dongfeng Gu | Zendy

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Novel Genetic Variation in Exon 28 of FBN1 Gene Is Associated With Essential Hypertension

Author(s) -

Chong Shen,

Xiangfeng Lu,

Laiyuan Wang,

Shufeng Chen,

Yun Li,

Xiaoli Liu,

Jianxin Li,

Jianfeng Huang,

Dongfeng Gu

Publication year - 2011

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1038/ajh.2011.21

Subject(s) - single nucleotide polymorphism , haplotype , essential hypertension , genetics , odds ratio , allele , genotype , candidate gene , medicine , genetic variation , confidence interval , genetic model , biology , gene , blood pressure

Recently, fibrillin-1 (FBN1) was reported to play an important role in maintaining the physiological arterial stiffness of essential hypertension (EH). Here, we designed a two-stage case-control study to investigate whether the FBN1 gene harbored any genetic variations associated with EH.

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