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Recently, fibrillin-1 (FBN1) was reported to play an important role in maintaining the physiological arterial stiffness of essential hypertension (EH). Here, we designed a two-stage case-control study to investigate whether the FBN1 gene harbored any genetic variations associated with EH.

Novel Genetic Variation in Exon 28 of FBN1 Gene Is Associated With Essential Hypertension