The ACE I/D Polymorphism in US Adults: Limited Evidence of Association With Hypertension-Related Traits and Sex-Specific Effects by Race/Ethnicity | Zendy

Renée M. Ned | Zendy; Ajay Yesupriya | Zendy; Giuseppina Imperatore | Zendy; Diane T. Smelser | Zendy; Ramal Moonesinghe | Zendy; ManHuei Chang | Zendy; Nicole F. Dowling | Zendy

Open Access

The ACE I/D Polymorphism in US Adults: Limited Evidence of Association With Hypertension-Related Traits and Sex-Specific Effects by Race/Ethnicity

Author(s) -

Renée M. Ned,

Ajay Yesupriya,

Giuseppina Imperatore,

Diane T. Smelser,

Ramal Moonesinghe,

ManHuei Chang,

Nicole F. Dowling

Publication year - 2011

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1038/ajh.2011.182

Subject(s) - national health and nutrition examination survey , medicine , blood pressure , ethnic group , demography , genotype , population , allele , polymorphism (computer science) , genetics , gene , biology , environmental health , sociology , anthropology

The insertion/deletion (I/D) variant (rs4646994) of the angiotensin I-converting enzyme (ACE) gene is one of the most studied polymorphisms in relation to blood pressure and essential hypertension in humans. The evidence to date, however, on an association of this variant with blood pressure-related outcomes has been inconclusive.

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