Impaired Endothelial Responses in Apparently Healthy Young People Associated With Subclinical Variation in Blood Pressure and Cardiovascular Phenotype | Zendy

Merzaka Lazdam | Zendy; Adam J. Lewandowski | Zendy; Ilias Kylintireas | Zendy; Colin Cunnington | Zendy; Jonathan Diesch | Zendy; J Francis | Zendy; Chris Trevitt | Zendy; Stefan Neubauer | Zendy; Ash Singhal | Zendy; Paul Leeson | Zendy

Open Access

Impaired Endothelial Responses in Apparently Healthy Young People Associated With Subclinical Variation in Blood Pressure and Cardiovascular Phenotype

Author(s) -

Merzaka Lazdam,

Adam J. Lewandowski,

Ilias Kylintireas,

Colin Cunnington,

Jonathan Diesch,

J Francis,

Chris Trevitt,

Stefan Neubauer,

Ash Singhal,

Paul Leeson

Publication year - 2011

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1038/ajh.2011.176

Subject(s) - medicine , blood pressure , brachial artery , arterial stiffness , endothelial dysfunction , cardiology , intima media thickness , pulse wave velocity , subclinical infection , pulse pressure , endothelium , endocrinology , carotid arteries

A phenomenon of endothelial impairment, independent of classical cardiovascular risk factors, has been observed in young people. We identified subjects with persistently reduced, or declining, endothelial function during adolescence and early adulthood, without apparent cardiovascular risk, and investigated the clinical relevance of this finding.

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