Arterial Stiffening, Wave Reflection, and Inflammation in Habitually Exercising Systemic Lupus Erythematosus Patients | Zendy

Jill N. Barnes | Zendy; Nantinee Nualnim | Zendy; Jun Sugawara | Zendy; Shawn M. Sommerlad | Zendy; C. P. Renzi | Zendy; Hirofumi Tanaka | Zendy

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Arterial Stiffening, Wave Reflection, and Inflammation in Habitually Exercising Systemic Lupus Erythematosus Patients

Author(s) -

Jill N. Barnes,

Nantinee Nualnim,

Jun Sugawara,

Shawn M. Sommerlad,

C. P. Renzi,

Hirofumi Tanaka

Publication year - 2011

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1038/ajh.2011.143

Subject(s) - medicine , arterial stiffness , systemic inflammation , body mass index , inflammation , population , pulse wave velocity , lupus erythematosus , cardiology , risk factor , immunology , gastroenterology , blood pressure , antibody , environmental health

Chronic systemic inflammation has been implicated in the pathogenesis of hypertension and cardiovascular disease. Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by chronic inflammation and an increased risk for cardiovascular disease. Currently few studies have evaluated the potential cardiovascular benefits of exercise in SLE. It is unknown whether the favorable effect of habitual exercise on arterial stiffness observed in healthy adults can be extended to SLE. Therefore, as an initial step, we determined the association between habitual exercise, inflammatory markers, central arterial compliance, and aortic wave reflection in healthy adults and SLE patients.

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