Phenylethanolamine N-Methyltransferase Gene Promoter Haplotypes and Risk of Essential Hypertension | Zendy

Cheng Huang | Zendy; Saidan Zhang | Zendy; Ke Hu | Zendy; Qilin Ma | Zendy; Tianlun Yang | Zendy

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Phenylethanolamine N-Methyltransferase Gene Promoter Haplotypes and Risk of Essential Hypertension

Author(s) -

Cheng Huang,

Saidan Zhang,

Ke Hu,

Qilin Ma,

Tianlun Yang

Publication year - 2011

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1038/ajh.2011.124

Subject(s) - medicine , phenylethanolamine n methyltransferase , haplotype , essential hypertension , gene , phenylethanolamine , genetics , blood pressure , pharmacology , endocrinology , bioinformatics , allele , biology , tyrosine hydroxylase , dopamine

Phenylethanolamine N-methyltransferase gene (PNMT) catalyzes the synthesis of epinephrine and plays an important role in regulating cardiovascular function. Genetic variation in the PNMT promoter is reportedly associated with the risk of essential hypertension in certain population.

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