Nitric Oxide and Reactive Hyperemia: Role of Location and Duration of Ischemia | Zendy

Ulrike Raff | Zendy; ClausEric Ott | Zendy; Stefan John | Zendy; Bernhard M.W. Schmidt | Zendy; Erwin H. Fleischmann | Zendy; R. Schmieder | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Nitric Oxide and Reactive Hyperemia: Role of Location and Duration of Ischemia

Author(s) -

Ulrike Raff,

ClausEric Ott,

Stefan John,

Bernhard M.W. Schmidt,

Erwin H. Fleischmann,

R. Schmieder

Publication year - 2010

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1038/ajh.2010.72

Subject(s) - medicine , ischemia , reactive hyperemia , anesthesia , saline , forearm , blood pressure , blood flow , surgery

Ischemia-induced reactive hyperemia (RH) is mediated by various factors including release of nitric oxide (NO). The contribution of NO to RH equals the extent of L-NMMA-dependent reduction of forearm blood flow (FBF). Because the optimal duration and location of ischemia that provokes maximum NO activation is unknown, we analyzed which duration and location stimulates most NO release, aiming at developing a noninvasive tool to measure endothelial integrity by NO synthase activity in humans.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research