Cardiovascular Responses to Aversive and Nonaversive Stressors in Schlager Genetically Hypertensive Mice | Zendy

Pamela J. Davern | Zendy; Kristy L. Jackson | Zendy; T.-P. Nguyen-Huu | Zendy; Luisa La Greca | Zendy; Geoffrey A. Head | Zendy

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Cardiovascular Responses to Aversive and Nonaversive Stressors in Schlager Genetically Hypertensive Mice

Author(s) -

Pamela J. Davern,

Kristy L. Jackson,

T.-P. Nguyen-Huu,

Luisa La Greca,

Geoffrey A. Head

Publication year - 2010

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1038/ajh.2010.69

Subject(s) - medicine , blood pressure , stressor , arousal , endocrinology , sympathetic nervous system , pressor response , shaker , aversive stimulus , tachycardia , heart rate , neuroscience , psychology , psychiatry , physics , quantum mechanics , vibration

Schlager inbred hypertensive mice (BPH/2J) have been suggested to have high blood pressure (BP) due to an overactive sympathetic nervous system (SNS). The brain nuclei associated with the hypertension are also those involved in the integration of the cardiovascular responses to stress. Therefore, in the present study, we hypothesize that an increased contribution of the SNS in BPH/2J mice may culminate in a greater pressor response to stressful stimuli in these hypertensive mice than normotensive (BPN/3J) mice.

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