Associations of the -344 T>C and the 3097 G>A Polymorphisms of CYP11B2 Gene With Hypertension, Type 2 Diabetes, and Metabolic Syndrome in a French Population | Zendy

N. Bellili | Zendy; L. Foucan | Zendy; Frédéric Fumeron | Zendy; Kamel Mohammedi | Zendy; F. Travert | Zendy; Ronan Roussel | Zendy; Beverley Balkau | Zendy; Jean Tichet | Zendy; Michel Marre | Zendy

Open Access

Associations of the -344 T>C and the 3097 G>A Polymorphisms of CYP11B2 Gene With Hypertension, Type 2 Diabetes, and Metabolic Syndrome in a French Population

Author(s) -

N. Bellili,

L. Foucan,

Frédéric Fumeron,

Kamel Mohammedi,

F. Travert,

Ronan Roussel,

Beverley Balkau,

Jean Tichet,

Michel Marre

Publication year - 2010

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1038/ajh.2010.44

Subject(s) - medicine , genotype , type 2 diabetes , haplotype , metabolic syndrome , odds ratio , endocrinology , population , diabetes mellitus , insulin resistance , gastroenterology , genetics , biology , gene , environmental health

Aldosterone can affect both blood pressure (BP) and glucose metabolism. We assessed the association of two polymorphisms -344 T>C and the 3097 G>A in the aldosterone synthase gene (CYP11B2) with prevalent and incident hypertension (HT), type 2 diabetes (T2D), and the metabolic syndrome (MetS).

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