Association of Osteoprotegerin With Aortic Stiffness in Patients With Symptomatic Peripheral Artery Disease and in Healthy Subjects | Zendy

Maksim Zagura | Zendy; Martin Serg | Zendy; Priit Kampus | Zendy; Mihkel Zilmer | Zendy; Kersti Zilmer | Zendy; Jaan Eha | Zendy; Eve Unt | Zendy; J. Lieberg | Zendy; Jaak Kals | Zendy

Open Access

Association of Osteoprotegerin With Aortic Stiffness in Patients With Symptomatic Peripheral Artery Disease and in Healthy Subjects

Author(s) -

Maksim Zagura,

Martin Serg,

Priit Kampus,

Mihkel Zilmer,

Kersti Zilmer,

Jaan Eha,

Eve Unt,

J. Lieberg,

Jaak Kals

Publication year - 2010

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1038/ajh.2010.38

Subject(s) - medicine , arterial stiffness , pulse wave velocity , osteoprotegerin , cardiology , peripheral , confounding , arterial disease , radial artery , blood pressure , vascular disease , artery , receptor , activator (genetics)

Arterial stiffening is an independent predictor for cardiovascular mortality. Preliminary studies have shown that arterial calcification may have an impact on increased vascular stiffness. However, there are limited data about the role of calcification inhibitor osteoprotegerin (OPG) as an independent predictor for arterial stiffness in patients with peripheral arterial disease (PAD) and in healthy subjects. The aim of this study was to evaluate the association between OPG and arterial stiffness parameters in patients with PAD and in healthy subjects.

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