Serum Uric Acid Levels and Renal Damage in Hyperuricemic Hypertensive Patients Treated With Renin-Angiotensin System Blockers | Zendy

Andrea Berni | Zendy; Maria Boddi | Zendy; Ermanna Fattori | Zendy; Ilaria Cecioni | Zendy; S. Berardino | Zendy; F. Montuschi | Zendy; Marco Chiostri | Zendy; Loredana Poggesi | Zendy

Open Access

Serum Uric Acid Levels and Renal Damage in Hyperuricemic Hypertensive Patients Treated With Renin-Angiotensin System Blockers

Author(s) -

Andrea Berni,

Maria Boddi,

Ermanna Fattori,

Ilaria Cecioni,

S. Berardino,

F. Montuschi,

Marco Chiostri,

Loredana Poggesi

Publication year - 2010

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1038/ajh.2010.33

Subject(s) - medicine , renal function , endocrinology , hyperuricemia , uric acid , urology , odds ratio , renin–angiotensin system , creatinine , blood pressure

A correlation between hyperuricemia and renal target organ damage (TOD) was shown in hypertensive patients, locally mediated by the activation of renin-angiotensin system (RAS). We investigated whether high serum uric acid (UA) levels could negatively affect tubulointerstitial damage in hyperuricemic essential hypertensive patients with normal renal function, on treatment with RAS-blocking drugs.

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