Reversal of Experimental Renovascular Hypertension Restores Coronary Microvascular Function and Architecture
Author(s) -
Victor H. Urbieta-Caceres,
Xingen Zhu,
Matthew E. Gibson,
Frédéric Favreau,
Karin Jordan,
A. Lerman,
Lilach O. Lerman
Publication year - 2011
Publication title -
american journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.009
H-Index - 136
eISSN - 1941-7225
pISSN - 0895-7061
DOI - 10.1038/ajh.2010.259
Subject(s) - medicine , renovascular hypertension , cardiology , blood pressure
Hypertension (HTN) may lead to left ventricular hypertrophy and vascular dysfunction, which are independent factors for adverse cardiovascular outcomes. We hypothesized that decreased blood pressure by percutaneous transluminal renal angioplasty (PTRA) would improve the function and architecture of coronary microvessels, in association with decreased inflammation and fibrosis.
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