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Urinary Albumin Excretion During Angiotensin II Receptor Blockade: Comparison of Combination Treatment With a Diuretic or a Calcium-Channel Blocker
Author(s) -
Yoshio Matsui,
Katsumi Eguchi,
Joji Ishikawa,
Kazuyuki Shimada,
Kazuomi Kario
Publication year - 2010
Publication title -
american journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.009
H-Index - 136
eISSN - 1941-7225
pISSN - 0895-7061
DOI - 10.1038/ajh.2010.240
Subject(s) - olmesartan , medicine , hydrochlorothiazide , endocrinology , blood pressure , diuretic , angiotensin receptor , urology , candesartan , creatinine , calcium channel blocker , angiotensin ii , pharmacology
We aimed to test the hypothesis that the angiotensin II receptor blocker (ARB)/diuretic combination decreases the urinary albumin/creatinine ratio (UACR) to a greater extent than treatment with the ARB/calcium-channel blocker (CCB) combination through a mechanism related to a greater reduction of sleep blood pressure (BP).

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