Toll-Like Receptor 6 Ser249Pro Polymorphism Is Associated With Lower Left Ventricular Wall Thickness and Inflammatory Response in Hypertensive Women | Zendy

Mariana Lázaro Sales | Zendy; Roberto Schreiber | Zendy; Maria C. Ferreira-Sae | Zendy; MFGM Fernandes | Zendy; Cristiane S.C. Piveta | Zendy; José A. Cipolli | Zendy; Cynthia Chester Cardoso | Zendy; José R. MatosSouza | Zendy; Bruno Geloneze | Zendy; Kleber G. Franchini | Zendy; Wilson Nadruz | Zendy

Open Access

Toll-Like Receptor 6 Ser249Pro Polymorphism Is Associated With Lower Left Ventricular Wall Thickness and Inflammatory Response in Hypertensive Women

Author(s) -

Mariana Lázaro Sales,

Roberto Schreiber,

Maria C. Ferreira-Sae,

MFGM Fernandes,

Cristiane S.C. Piveta,

José A. Cipolli,

Cynthia Chester Cardoso,

José R. MatosSouza,

Bruno Geloneze,

Kleber G. Franchini,

Wilson Nadruz

Publication year - 2010

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1038/ajh.2010.24

Subject(s) - medicine , zymosan , interventricular septum , allele , endocrinology , agonist , genotype , receptor , immunology , biology , gene , genetics , ventricle , in vitro

Experimental data demonstrated that inactivation of toll-like receptor (TLR) pathway components attenuated left ventricular (LV) remodeling induced by pressure overload. This study investigated the impact of TLR6 Ser249Pro polymorphism on LV structure in hypertensive subjects.

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