Globular and Full-Length Adiponectin Induce NO-Dependent Vasodilation in Resistance Arteries of Zucker Lean but Not Zucker Diabetic Fatty Rats
Author(s) -
P. Schmid,
Markus Resch,
Andreas Steege,
Sabine Fredersdorf-Hahn,
Benjamin Stoelcker,
Christoph Birner,
Christian Schach,
Christa Buechler,
Günter A.J. Riegger,
Andreas Luchner,
Dierk Endemann
Publication year - 2010
Publication title -
american journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.009
H-Index - 136
eISSN - 1941-7225
pISSN - 0895-7061
DOI - 10.1038/ajh.2010.239
Subject(s) - adiponectin , medicine , endocrinology , vasodilation , mesenteric arteries , adiponectin receptor 1 , insulin resistance , enos , nitric oxide , diabetes mellitus , nitric oxide synthase , artery
Adiponectin increases nitric oxide (NO) production in endothelial cell cultures and is reduced in the circulation of obese and diabetic patients, but its functional effect on resistance arteries is not yet studied in detail.
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