Daily Red Wine Consumption Improves Vascular Function by a Soluble Guanylyl Cyclase-Dependent Pathway | Zendy

Ilse P.G. Botden | Zendy; Janneke G. Langendonk | Zendy; Marcel E. Meima | Zendy; Frans Boomsma | Zendy; Ann L.B. Seynhaeve | Zendy; Timo L.M. ten Hagen | Zendy; A.H. Jan Danser | Zendy; Eric J.G. Sijbrands | Zendy

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Daily Red Wine Consumption Improves Vascular Function by a Soluble Guanylyl Cyclase-Dependent Pathway

Author(s) -

Ilse P.G. Botden,

Janneke G. Langendonk,

Marcel E. Meima,

Frans Boomsma,

Ann L.B. Seynhaeve,

Timo L.M. ten Hagen,

A.H. Jan Danser,

Eric J.G. Sijbrands

Publication year - 2010

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1038/ajh.2010.227

Subject(s) - bradykinin , medicine , soluble guanylyl cyclase , wine , sodium nitroprusside , endothelium , nitric oxide , vasodilation , cyclic guanosine monophosphate , myograph , endocrinology , vascular smooth muscle , pharmacology , food science , chemistry , guanylate cyclase , receptor , smooth muscle

Polyphenols in red wine are supposed to improve endothelial function. We investigated whether daily red wine consumption improves in-vivo vascular function by reducing endothelin-1 (ET-1). Additional pathways mediating this effect were studied using porcine coronary arteries (PCAs).

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