Tyrosine Hydroxylase Polymorphism (C-824T) and Hypertension: A Population-Based Study | Zendy

Samara Joy Nielsen | Zendy; Jesper Jeppesen | Zendy; C. TorpPedersen | Zendy; Tine W. Hansen | Zendy; Allan Linneberg | Zendy; Mogens Fenger | Zendy

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Tyrosine Hydroxylase Polymorphism (C-824T) and Hypertension: A Population-Based Study

Author(s) -

Samara Joy Nielsen,

Jesper Jeppesen,

C. TorpPedersen,

Tine W. Hansen,

Allan Linneberg,

Mogens Fenger

Publication year - 2010

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1038/ajh.2010.165

Subject(s) - medicine , genotype , blood pressure , single nucleotide polymorphism , ambulatory blood pressure , essential hypertension , snp , population , endocrinology , tyrosine hydroxylase , polymorphism (computer science) , ambulatory , heart rate , diastole , genetics , biology , gene , environmental health , dopamine

Sympathetic nervous system (SNS) overactivity is present in a large proportion of the hypertensive population and precedes the development of established hypertension. Variations in the proximal promoter of the tyrosine hydroxylase (TH) gene have been shown to influence biochemical and physiological traits in the SNS as well as hypertension.

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