Plasma C-Terminal Pro-Endothelin-1 Is Associated With Target-Organ Damage in African Americans With Hypertension | Zendy

Ammar Habib | Zendy; Malik A. Al-Omari | Zendy; Mahyar Khaleghi | Zendy; Nils G. Morgenthaler | Zendy; Joachim Struck | Zendy; Andreas Bergmann | Zendy; Thomas H. Mosley | Zendy; Stephen T. Turner | Zendy; Iftikhar J. Kullo | Zendy

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Plasma C-Terminal Pro-Endothelin-1 Is Associated With Target-Organ Damage in African Americans With Hypertension

Author(s) -

Ammar Habib,

Malik A. Al-Omari,

Mahyar Khaleghi,

Nils G. Morgenthaler,

Joachim Struck,

Andreas Bergmann,

Thomas H. Mosley,

Stephen T. Turner,

Iftikhar J. Kullo

Publication year - 2010

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1038/ajh.2010.149

Subject(s) - medicine , blood pressure , body mass index , renal function , diabetes mellitus , endocrinology , creatinine , kidney disease , cardiology

Endothelin-1 (ET-1) is a vasoactive peptide with vasoconstrictor and mitogenic properties. We investigated whether plasma levels of C-terminal pro-ET-1 (CT-proET-1), a newly described stable fragment of the ET-1 precursor, are associated with target-organ damage in hypertension.

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