Association Between the G Protein 3 Subunit C825T Polymorphism and the Occurrence of Cardiovascular Disease in Hypertensives: The Nord-Trondelag Health Study (HUNT)
Author(s) -
Oddgeir L. Holmen,
Solfrid Romundstad,
Øyvind Melien
Publication year - 2010
Publication title -
american journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.009
H-Index - 136
eISSN - 1941-7225
pISSN - 0895-7061
DOI - 10.1038/ajh.2010.121
Subject(s) - medicine , norwegian , disease , polymorphism (computer science) , genetics , demography , genotype , biology , philosophy , linguistics , sociology , gene
Several studies examining the C825T polymorphism of the G protein β3 subunit (GNB3) have shown inconsistent results regarding susceptibility to hypertension. With twice the length of earlier studies, the aim of our study was to further investigate this association with a cross-sectional design over an 11.5-year follow-up period in a Norwegian population.
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