Chronic Antioxidant Treatment Improves Arterial Renovascular Hypertension and Oxidative Stress Markers in the Kidney in Wistar Rats
Author(s) -
Érika E. Nishi,
Elizabeth Barbosa OliveiraSales,
Cássia T. Bergamaschi,
T. G. C. Oliveira,
M. A. Boim,
Ruy R. Campos
Publication year - 2010
Publication title -
american journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.009
H-Index - 136
eISSN - 1941-7225
pISSN - 0895-7061
DOI - 10.1038/ajh.2010.11
Subject(s) - medicine , oxidative stress , renovascular hypertension , antioxidant , kidney , cardiology , endocrinology , biochemistry , chemistry
Sympathetic vasomotor hyperactivity and baroreflex dysfunction are involved in the development and maintenance of renovascular arterial hypertension. We hypothesized that angiotensin (Ang) II-dependent oxidative stress contributes to the pathophysiology of the two-kidney, one-clip (2K-1C) model.
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