Ambulatory Blood Pressure Control With Bedtime Aspirin Administration in Subjects With Prehypertension | Zendy

R. C. Hermida | Zendy; D. E. Ayala | Zendy; Artemio Mojón | Zendy; José R. Fernández | Zendy

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Ambulatory Blood Pressure Control With Bedtime Aspirin Administration in Subjects With Prehypertension

Author(s) -

R. C. Hermida,

D. E. Ayala,

Artemio Mojón,

José R. Fernández

Publication year - 2009

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1038/ajh.2009.83

Subject(s) - bedtime , medicine , aspirin , prehypertension , blood pressure , ambulatory , ambulatory blood pressure , heart rate , crossover study , anesthesia , cardiology , placebo , alternative medicine , pathology

Aspirin has been found to prevent angiotensin II-induced hypertension and to induce nitric oxide (NO) release from vascular endothelium. Low-dose aspirin has also been shown to reduce blood pressure (BP) when administered at bedtime, as opposed to upon awakening, in untreated hypertensive patients and high-risk pregnant women. Accordingly, we investigated the effects on ambulatory BP of aspirin administered at different times of the day in prehypertension.

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