Genetic and Pharmacogenetic Associations Between NOS3 Polymorphisms, Blood Pressure, and Cardiovascular Events in Hypertension | Zendy

Michael Pacanowski | Zendy; Issam Zineh | Zendy; Rhonda M. Cooper-DeHoff | Zendy; Carl J. Pepine | Zendy; Julie A. Johnson | Zendy

Open Access

Genetic and Pharmacogenetic Associations Between NOS3 Polymorphisms, Blood Pressure, and Cardiovascular Events in Hypertension

Author(s) -

Michael Pacanowski,

Issam Zineh,

Rhonda M. Cooper-DeHoff,

Carl J. Pepine,

Julie A. Johnson

Publication year - 2009

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1038/ajh.2009.81

Subject(s) - medicine , pharmacogenetics , blood pressure , cardiovascular event , polymorphism (computer science) , cardiology , genotype , pharmacology , bioinformatics , genetics , gene , disease , biology

Polymorphisms in the endothelial nitric oxide synthase (NOS3) gene increase susceptibility to hypertension and cardiovascular disease. We examined genetic and pharmacogenetic associations between NOS3 polymorphisms, blood pressure (BP) control, and cardiovascular events in elderly, hypertensive coronary artery disease (CAD) patients.

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