Insular Cortex Atrophy as an Independent Determinant of Disrupted Diurnal Rhythm of Ambulatory Blood Pressure in Elderly Hypertension
Author(s) -
Michiaki Nagai,
Satoshi Hoshide,
Jun Ishikawa,
K. Shimada,
Kazuomi Kario
Publication year - 2009
Publication title -
american journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.009
H-Index - 136
eISSN - 1941-7225
pISSN - 0895-7061
DOI - 10.1038/ajh.2009.71
Subject(s) - medicine , atrophy , ambulatory blood pressure , endocrinology , ambulatory , blood pressure , insular cortex , circadian rhythm , magnetic resonance imaging , body mass index , cardiology , radiology , psychiatry
Insular cortex (Ic) has been suggested to be a key site in limbic-autonomic integration. Association of Ic damage with disruption of diurnal blood pressure (BP) variation and higher serum level of noradrenaline has been reported. We examined the relationships of Ic volume with ambulatory BP measures and noradrenaline concentration.
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