Variation in Renin-Angiotensin System and Salt-Sensitivity Genes and the Risk of Diabetes Mellitus Associated With the Use of Thiazide Diuretics | Zendy

Özlem Bozkurt | Zendy; Anthonius de Boer | Zendy; D. E. Grobbee | Zendy; Peter W. de Leeuw | Zendy; Abraham A. Kroon | Zendy; Paul Schiffers | Zendy; Olaf H. Klungel | Zendy

Open Access

Variation in Renin-Angiotensin System and Salt-Sensitivity Genes and the Risk of Diabetes Mellitus Associated With the Use of Thiazide Diuretics

Author(s) -

Özlem Bozkurt,

Anthonius de Boer,

D. E. Grobbee,

Peter W. de Leeuw,

Abraham A. Kroon,

Paul Schiffers,

Olaf H. Klungel

Publication year - 2009

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1038/ajh.2009.38

Subject(s) - medicine , thiazide , diabetes mellitus , endocrinology , odds ratio , hydrochlorothiazide , type 2 diabetes , allele , diuretic , blood pressure , genetics , gene , biology

Variation in the renin-angiotensin system (RAS) and salt-sensitivity genes may influence the effect of thiazides on the risk of diabetes. We assessed whether polymorphisms in RAS and salt-sensitivity genes influenced the risk of diabetes associated with thiazides.

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