Genetic Polymorphism on Type 2 Receptor of Angiotensin II, Modifies Cardiovascular Risk And Systemic Inflammation in Hypertensive Males | Zendy

Dimitris Tousoulis | Zendy; Nikolas Koumallos | Zendy; Charalambos Antoniades | Zendy; Alexios S. Antonopoulos | Zendy; Constantinos Bakogiannis | Zendy; Antigoni Milliou | Zendy; Kiriakoula Marinou | Zendy; Eftihia Kallikazarou | Zendy; Elli Stefanadi | Zendy; D. Mentzikof | Zendy; Christodoulos Stefanadis | Zendy

Open Access

Genetic Polymorphism on Type 2 Receptor of Angiotensin II, Modifies Cardiovascular Risk And Systemic Inflammation in Hypertensive Males

Author(s) -

Dimitris Tousoulis,

Nikolas Koumallos,

Charalambos Antoniades,

Alexios S. Antonopoulos,

Constantinos Bakogiannis,

Antigoni Milliou,

Kiriakoula Marinou,

Eftihia Kallikazarou,

Elli Stefanadi,

D. Mentzikof,

Christodoulos Stefanadis

Publication year - 2009

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1038/ajh.2009.233

Subject(s) - medicine , fibrinogen , coronary artery disease , endocrinology , odds ratio , allele , angiotensin ii , blood pressure , population , immunology , genetics , gene , biology , environmental health

Angiotensin type 2 receptor (AT2R), plays a crucial role in blood pressure regulation and atherogenesis. AT2R gene is located on chromosome X and the biological effect of polymorphism A1675G in this gene needs to be further specified. We examined the impact of A1675G on the risk and the severity of coronary artery disease (CAD), and the expression of proatherogenic inflammatory molecules in hypertensive patients.

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