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Hypertension is more common among men at younger ages and among women after age 60, suggesting a possible link between endogenous estrogens and systolic blood pressure (SBP). We tested whether serum 17beta-estradiol (E(2)) or any of its metabolites were associated with SBP among middle-aged and older adults.

Serum Estrogen Metabolites and Systolic Blood Pressure Among Middle-Aged and Older Women and Men