Soluble CD40 Ligand Levels in Essential Hypertensive Men: Evidence of a Possible Role of Insulin Resistance | Zendy

G Penno | Zendy; Laura Pucci | Zendy; Giacomo Dell’Omo | Zendy; Daniela Lucchesi | Zendy; Roberto Miccoli | Zendy; Stefano Del Prato | Zendy; Anna Solini | Zendy; Roberto Pedrinelli | Zendy

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Soluble CD40 Ligand Levels in Essential Hypertensive Men: Evidence of a Possible Role of Insulin Resistance

Author(s) -

G Penno,

Laura Pucci,

Giacomo Dell’Omo,

Daniela Lucchesi,

Roberto Miccoli,

Stefano Del Prato,

Anna Solini,

Roberto Pedrinelli

Publication year - 2009

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1038/ajh.2009.121

Subject(s) - medicine , insulin resistance , endocrinology , interquartile range , insulin , blood pressure , diabetes mellitus , metabolic syndrome , intima media thickness , basal (medicine) , body mass index , homeostasis , albuminuria , proinflammatory cytokine , type 2 diabetes , inflammation , carotid arteries

Elevated levels of the proinflammatory cytokine soluble CD40 ligand (sCD40L) were reported in subjects with diabetes, impaired glucose tolerance, metabolic syndrome (MS), obesity, and insulin resistance. Metabolic abnormalities might also account for increased sCD40L in subjects with essential hypertension.

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