Open AccessNovel Genetic Variants in the α-Adducin and Guanine Nucleotide Binding Protein β-Polypeptide 3 Genes and Salt Sensitivity of Blood Pressure
Author(s) -
Tanika N. Kelly,
Treva Rice,
Dongfeng Gu,
James E. Hixson,
Jing Chen,
DePei Liu,
Cashell E. Jaquish,
Lydia Bazzano,
Dongsheng Hu,
Jixiang Ma,
C. Charles Gu,
Jianfeng Huang,
L. Lee Hamm,
Jiang He
Publication year - 2009
Publication title -
american journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.009
H-Index - 136
eISSN - 1941-7225
pISSN - 0895-7061
DOI - 10.1038/ajh.2009.118
Subject(s) - single nucleotide polymorphism , blood pressure , medicine , allele , endocrinology , sodium , mean arterial pressure , genotype , gene , genetics , biology , chemistry , heart rate , organic chemistry
We examined the association between 12 single-nucleotide polymorphisms (SNPs) in the alpha-adducin (ADD1) and guanine nucleotide binding protein (G protein) beta-polypeptide 3 (GNB3) genes and systolic (SBP), diastolic (DBP), and mean arterial (MAP) pressure responses to salt intake.
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