Assessment of Genetic Risk Factors for Thoracic Aortic Aneurysm in Hypertensive Patients | Zendy

Kimihiko Kato | Zendy; Mitsutoshi Oguri | Zendy; Noriyuki Kato | Zendy; Takeshi Hibino | Zendy; Kazuhiro Yajima | Zendy; Tetsuro Yoshida | Zendy; Norifumi Metoki | Zendy; Hidemi Yoshida | Zendy; Kei Satoh | Zendy; Sachiro Watanabe | Zendy; Kiyoshi Yokoi | Zendy; Toyoaki Murohara | Zendy; Yoshiji Yamada | Zendy

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Assessment of Genetic Risk Factors for Thoracic Aortic Aneurysm in Hypertensive Patients

Author(s) -

Kimihiko Kato,

Mitsutoshi Oguri,

Noriyuki Kato,

Takeshi Hibino,

Kazuhiro Yajima,

Tetsuro Yoshida,

Norifumi Metoki,

Hidemi Yoshida,

Kei Satoh,

Sachiro Watanabe,

Kiyoshi Yokoi,

Toyoaki Murohara,

Yoshiji Yamada

Publication year - 2008

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1038/ajh.2008.229

Subject(s) - odds ratio , medicine , genotype , gpx1 , allele , polymorphism (computer science) , aortic aneurysm , gastroenterology , genetics , oncology , gene , biology , aorta , glutathione peroxidase , catalase , oxidative stress

Conventional risk factors for thoracic aortic aneurysm including dissection (TAA) are thought to include age, arteriosclerosis, and hypertension. In addition, evidence suggests that genetic factors play a role in the development of this condition. The purpose of the present study was to identify genetic variants that confer susceptibility to TAA in hypertensive subjects.

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