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Cigarette Smoke Exposure and Angiogenic Factors in Pregnancy and Preeclampsia
Author(s) -
Arundhathi Jeyabalan,
Robert W. Powers,
Allison R. Durica,
Gail Harger,
James M. Roberts,
R. B. Ness
Publication year - 2008
Publication title -
american journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.009
H-Index - 136
eISSN - 1941-7225
pISSN - 0895-7061
DOI - 10.1038/ajh.2008.219
Subject(s) - medicine , preeclampsia , placental growth factor , cotinine , pregnancy , soluble fms like tyrosine kinase 1 , nicotine , obstetrics , cigarette smoking , cigarette smoke , endocrinology , vascular endothelial growth factor , vegf receptors , genetics , environmental health , biology
Cigarette smoking during pregnancy is paradoxically associated with a reduced risk of developing preeclampsia. Both smoking and preeclampsia are associated with alterations in circulating angiogenic factors. The objective of this study was to investigate the relationship between cigarette smoking and the angiogenic factors soluble fms-like tyrosine kinase-1 (sFlt-1) and placental growth factor (PlGF) in pregnant women with and without preeclampsia.

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