Open AccessAssociation of a Polymorphism in the Lipin 1 Gene With Systolic Blood Pressure in Men
Author(s) -
Kwok Leung Ong,
R Leung,
LC Wong,
Stacey S. Cherny,
Pak Sham,
TaiHing Lam,
Karen Siu Ling Lam,
Bmy Cheung
Publication year - 2008
Publication title -
american journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.009
H-Index - 136
eISSN - 1941-7225
pISSN - 0895-7061
DOI - 10.1038/ajh.2008.21
Subject(s) - medicine , blood pressure , polymorphism (computer science) , systole , cardiology , gene , diastole , genetics , genotype , biology
Lipin 1 plays a role in abdominal obesity, insulin resistance, and hypertriglyceridemia. The gene is located at 2p25.1, a susceptibility locus for hypertension. We studied the association of tagging single-nucleotide polymorphisms (SNPs) in the lipin 1 (LPIN1) gene with hypertension and blood pressure.