Statin Treatment Improves Cerebral More Than Systemic Endothelial Dysfunction in Patients With Arterial Hypertension | Zendy

Janja Pretnar Oblak | Zendy; Miran Šebeštjen | Zendy; Mišo Šabovič | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Statin Treatment Improves Cerebral More Than Systemic Endothelial Dysfunction in Patients With Arterial Hypertension

Author(s) -

Janja Pretnar Oblak,

Miran Šebeštjen,

Mišo Šabovič

Publication year - 2008

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1038/ajh.2008.153

Subject(s) - medicine , atorvastatin , brachial artery , reactive hyperemia , cerebral circulation , cardiology , middle cerebral artery , endothelial dysfunction , cerebral blood flow , arginine , statin , cerebral arteries , endothelium , blood pressure , blood flow , ischemia , biochemistry , chemistry , amino acid

The pleiotropic effects of statins on the endothelial function are well recognized. However, the effect of statins might not be equally pronounced in the cerebral and systemic circulation. We compared cerebral and systemic endothelial function by L-arginine cerebrovascular reactivity and flow-mediated dilatation (FMD), respectively, in patients with arterial hypertension (AH) and healthy controls before and after atorvastatin treatment.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research