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Renal Response to Angiotensin II is Blunted in Sodium-sensitive Normotensive Men
Author(s) -
F. W. Visser,
Arnold H. Boonstra,
A. Titia Lely,
Frans Boomsma,
Gerjan Navis
Publication year - 2008
Publication title -
american journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.009
H-Index - 136
eISSN - 1941-7225
pISSN - 0895-7061
DOI - 10.1038/ajh.2007.63
Subject(s) - effective renal plasma flow , medicine , endocrinology , angiotensin ii , blood pressure , enalapril , renal function , renin–angiotensin system , renal blood flow , plasma renin activity , hemodynamics , sodium , aldosterone , renal circulation , mean arterial pressure , kidney , angiotensin converting enzyme , chemistry , heart rate , organic chemistry
In hypertension, sodium sensitivity (SS) of blood pressure is associated with renal hemodynamic abnormalities related to increased activity of the renal renin-angiotensin aldosterone system (RAAS). The renal mechanisms of SS in normotensives are unknown. Therefore, we studied whether SS is related to renal hemodynamics and renal responsiveness to angiotensin II (AngII) in young healthy adults.

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