A Twofold Genetic Increase of ACE Expression Has No Effect on the Development of Spontaneous Hypertension | Zendy

Ibrahim Nassar | Zendy; Angela Schulz | Zendy; Cátia Campaner Ferrari Bernardy | Zendy; Ingrid M. Garrelds | Zendy; Ralph Plehm | Zendy; Matthias Huber | Zendy; A.H. Jan Danser | Zendy; Reinhold Kreutz | Zendy

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A Twofold Genetic Increase of ACE Expression Has No Effect on the Development of Spontaneous Hypertension

Author(s) -

Ibrahim Nassar,

Angela Schulz,

Cátia Campaner Ferrari Bernardy,

Ingrid M. Garrelds,

Ralph Plehm,

Matthias Huber,

A.H. Jan Danser,

Reinhold Kreutz

Publication year - 2008

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1038/ajh.2007.38

Subject(s) - congenic , endocrinology , medicine , renin–angiotensin system , spontaneously hypertensive rat , kidney , angiotensin converting enzyme , plasma renin activity , messenger rna , blood pressure , angiotensin ii , renovascular hypertension , biology , gene , genetics

To study the regulation of a naturally occurring genetic variant of high angiotensin-converting enzyme (ACE) gene (Ace in rat) expression, i.e., the Ace allele of the normotensive Wistar-Kyoto (WKY) rat, in the hypertensive background of stroke-prone spontaneously hypertensive (SHRSP) rats.

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