Carryover Effects After Cessation of Drug Treatment: Trophies or Dreams?
Author(s) -
Thomas Lumley,
Kenneth Rice,
Bruce M. Psaty
Publication year - 2007
Publication title -
american journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.009
H-Index - 136
eISSN - 1941-7225
pISSN - 0895-7061
DOI - 10.1038/ajh.2007.21
Subject(s) - trophy , medicine , candesartan , blood pressure , placebo , cardiology , prehypertension , incidence (geometry) , angiotensin ii , pathology , physics , alternative medicine , optics , political science , law
In randomized trials of primary prevention, there has been interest in the persistence of a beneficial effect of therapy after treatment has been stopped. We investigated the impact of measurement error in the outcome on results of the trial of preventing hypertension (TROPHY), a trial of candesartan vs. placebo for preventing hypertension in prehypertensive subjects.
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