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Neuronal Nitric Oxide Synthase-Deficient Mice Have Impaired Renin Release But Normal Blood Pressure
Author(s) -
Johan Sällström,
Mattias Carlström,
Boye L. Jensen,
Ole Skøtt,
Russell D. Brown,
A. Erik G. Persson
Publication year - 2007
Publication title -
american journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.009
H-Index - 136
eISSN - 1941-7225
pISSN - 0895-7061
DOI - 10.1038/ajh.2007.16
Subject(s) - endocrinology , medicine , plasma renin activity , renin–angiotensin system , blood pressure , low sodium diet , nitric oxide , sodium , nitric oxide synthase , excretion , low sodium , radioimmunoassay , chemistry , organic chemistry
Nitric oxide deficiency is involved in the development of hypertension, but the mechanisms are currently unclear. This study was conducted to further elucidate the role of neuronal nitric oxide synthase (nNOS) in blood pressure regulation and renin release in relation to different sodium loads.

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