Upregulation of Endothelial and Inducible Nitric Oxide Synthase Expression by Reactive Oxygen Species | Zendy

Jiang Zhen | Zendy; Hua Lu | Zendy; X. Q. Wang | Zendy; N.D. Vaziri | Zendy; Xin Zhou | Zendy

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Upregulation of Endothelial and Inducible Nitric Oxide Synthase Expression by Reactive Oxygen Species

Author(s) -

Jiang Zhen,

Hua Lu,

X. Q. Wang,

N.D. Vaziri,

Xin Zhou

Publication year - 2007

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1038/ajh.2007.14

Subject(s) - enos , oxidative stress , superoxide , nitric oxide , glutathione , nitric oxide synthase , reactive oxygen species , xanthine oxidase , nitric oxide synthase type iii , medicine , buthionine sulfoximine , endocrinology , downregulation and upregulation , endothelial nos , biology , biochemistry , enzyme , gene

The effect of reactive oxygen species (ROS) on nitric oxide synthase (NOS) expression remains uncertain. This study explored the effect of increased ROS activity on NOS expression in vitro in human coronary artery endothelial cells (HCAECs) grown in culture and in intact animals.

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