Calcium Channel Blockers Suppress Cytokine-induced Activation of Human Neutrophils | Zendy

Etsuko Shima | Zendy; Motoki Katsube | Zendy; T. Kato | Zendy; Masahiro Kitagawa | Zendy; Fumihiko Hato | Zendy; Masayuki Hino | Zendy; Tsuyoshi Takahashi | Zendy; Hideaki Fujita | Zendy; Seiichi Kitagawa | Zendy

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Calcium Channel Blockers Suppress Cytokine-induced Activation of Human Neutrophils

Author(s) -

Etsuko Shima,

Motoki Katsube,

T. Kato,

Masahiro Kitagawa,

Fumihiko Hato,

Masayuki Hino,

Tsuyoshi Takahashi,

Hideaki Fujita,

Seiichi Kitagawa

Publication year - 2007

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1038/ajh.2007.13

Subject(s) - amlodipine , nicardipine , medicine , pharmacology , calcium channel , protein kinase b , endocrinology , mapk/erk pathway , verapamil , nifedipine , proinflammatory cytokine , calcium channel blocker , kinase , signal transduction , calcium , inflammation , biology , blood pressure , microbiology and biotechnology

Neutrophils, in concert with proinflammatory cytokines, play an important role in the progression of atherosclerosis. Calcium channel blockers are commonly used in the treatment of hypertension, and their pleiotropic effects, other than the lowering of blood pressure, have been recently recognized.

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