DNA methylation of NR3C1 and FKBP5 is associated with posttraumatic stress disorder, posttraumatic growth, and resilience. | Zendy

Olivia Miller | Zendy; Jane ShakespeareFinch | Zendy; Dagmar Bruenig | Zendy; Divya Mehta | Zendy

Open Access

DNA methylation of NR3C1 and FKBP5 is associated with posttraumatic stress disorder, posttraumatic growth, and resilience.

Author(s) -

Olivia Miller,

Jane ShakespeareFinch,

Dagmar Bruenig,

Divya Mehta

Publication year - 2020

Publication title -

psychological trauma theory research practice and policy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.059

H-Index - 48

eISSN - 1942-9681

pISSN - 1942-969X

DOI - 10.1037/tra0000574

Subject(s) - fkbp5 , posttraumatic stress , resilience (materials science) , dna methylation , posttraumatic growth , clinical psychology , psychology , medicine , glucocorticoid receptor , biology , genetics , gene , materials science , glucocorticoid , gene expression , composite material

Understandings of the biological mechanisms underpinning posttrauma responses are limited. This pilot study aimed to expand research in this area by examining the relationship between DNA methylation of stress genes nuclear receptor subfamily 3 group C member 1 ( NR3C1 ) and FK06 binding protein 5 ( FKBP5 ) with an array of posttrauma responses of posttraumatic stress disorder (PTSD) symptom severity, posttraumatic growth (PTG), and resilience.

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