Open AccessSmoking cessation with four nicotine replacement regimes in a lung clinic
Author(s) -
Tønnesen P.,
Mikkelsen K.L.
Publication year - 2000
Publication title -
european respiratory journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.021
H-Index - 241
eISSN - 1399-3003
pISSN - 0903-1936
DOI - 10.1034/j.1399-3003.2000.16d25.x
Subject(s) - medicine , smoking cessation , nicotine , nicotine patch , placebo , inhaler , nicotine replacement therapy , nicotine gum , anesthesia , physical therapy , asthma , alternative medicine , pathology
Smoking cessation is a key intervention for prevention of several lung diseases. The aim of the present study was to compare the effect of smoking cessation with nicotine replacement in a lung clinic in a low resource set‐up suitable for implementation in other lung clinics. This was an open, randomized trial with 4 different nicotine replacement regimes combined with minimal behavioural support in daily routine. A total of 446 smokers (>9 cigarettes·day ‐1 ) were allocated to a nurse‐conducted smoking cessation programme with 4 treatment arms: a 5‐mg nicotine patch (“placebo”), a 15‐mg nicotine patch, nicotine inhaler, and a 15‐mg nicotine patch plus nicotine inhaler. Recommended use of the nicotine products were 3 months with the possibility of continuing use up to 9 months on an individual basis. Individual follow‐up studies were scheduled after 2 and 6 weeks, 3, 6, 9 and 12 months. The 12‐month point prevalence was 6% (5‐mg patch (placebo)), 16% (15‐mg patch) (p<0.05), 9% (inhaler) and 11% (15‐mg patch plus inhaler), respectively. To conclude, the set‐up investigated in this study which included minimal beha‐vioural support with nicotine patches should be evaluated in other lung clinics, as it doubled success rate when compared to a placebo with a 1‐yr point prevalence of 16% and also the resources used are limited.