Crux: Rapid Open Source Protein Tandem Mass Spectrometry Analysis
Author(s) -
Sean McIlwain,
Kaipo Tamura,
Attila KertészFarkas,
Charles E. Grant,
Benjamin J. Diament,
Barbara Frewen,
James Jeffry Howbert,
Michael R. Hoopmann,
Lukas Käll,
Jimmy K. Eng,
Michael J. MacCoss,
William Stafford Noble
Publication year - 2014
Publication title -
journal of proteome research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.644
H-Index - 161
eISSN - 1535-3907
pISSN - 1535-3893
DOI - 10.1021/pr500741y
Subject(s) - suite , computer science , open source , mass spectrometry , tandem mass spectrometry , software , software suite , tandem mass tag , open source software , chemistry , proteomics , chromatography , quantitative proteomics , programming language , biochemistry , archaeology , gene , history
Efficiently and accurately analyzing big protein tandem mass spectrometry data sets requires robust software that incorporates state-of-the-art computational, machine learning, and statistical methods. The Crux mass spectrometry analysis software toolkit ( http://cruxtoolkit.sourceforge.net ) is an open source project that aims to provide users with a cross-platform suite of analysis tools for interpreting protein mass spectrometry data.
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