PhenoFluor: Practical Synthesis, New Formulation, and Deoxyfluorination of Heteroaromatics
Author(s) -
Teppei Fujimoto,
Fabian Becker,
Tobias Ritter
Publication year - 2014
Publication title -
organic process research and development
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 109
eISSN - 1520-586X
pISSN - 1083-6160
DOI - 10.1021/op500121w
Subject(s) - reagent , scope (computer science) , toluene , combinatorial chemistry , substrate (aquarium) , chemistry , computer science , organic chemistry , oceanography , programming language , geology
We report a practical synthesis method of the reagent PhenoFluor on decagram scale, provide a new formulation of PhenoFluor as a toluene solution, which should decrease challenges associated with the moisture sensitivity of the reagent, and expand the substrate scope of deoxyfluorination with PhenoFluor to heteroaromatics.
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