A Simple and Efficient Synthesis of 2,3-Diarylnaphthofurans Using Sequential Hydroarylation/Heck Oxyarylation | Zendy

V. Kameshwara Rao | Zendy; Ganesh M. Shelke | Zendy; Rakesh K. Tiwari | Zendy; Keykavous Parang | Zendy; Anil Kumar | Zendy

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A Simple and Efficient Synthesis of 2,3-Diarylnaphthofurans Using Sequential Hydroarylation/Heck Oxyarylation

Author(s) -

V. Kameshwara Rao,

Ganesh M. Shelke,

Rakesh K. Tiwari,

Keykavous Parang,

Anil Kumar

Publication year - 2013

Publication title -

organic letters

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.94

H-Index - 239

eISSN - 1523-7060

pISSN - 1523-7052

DOI - 10.1021/ol400738r

Subject(s) - chemistry , heck reaction , microwave irradiation , simple (philosophy) , combinatorial chemistry , microwave , organic chemistry , catalysis , palladium , computer science , telecommunications , philosophy , epistemology

An efficient and simple strategy has been developed for the synthesis of 2,3-diarylnaphthofurans using sequential hydroarylation of naphthols and alkynes in the presence of In(OTf)3 under microwave irradiation followed by one-pot Heck-oxyarylation of generated 1-substituted-α-hydroxy styrenes.

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