Open AccessTotal Synthesis of Paracaseolide A
Author(s) -
Tezcan Güney,
George A. Kraus
Publication year - 2013
Publication title -
organic letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.94
H-Index - 239
eISSN - 1523-7060
pISSN - 1523-7052
DOI - 10.1021/ol303447r
Subject(s) - chemistry , total synthesis , yield (engineering) , combinatorial chemistry , diversification (marketing strategy) , stereochemistry , business , materials science , marketing , metallurgy
The total synthesis of paracaseolide A, a valuable cell-cycle progression inhibitor, was accomplished in 8 steps from known compounds, with 6.6% overall yield. The synthetic strategy creates strong potential for diversification.
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