Open AccessA Rapid and Efficient Access to Diaryldibenzo[b,f][1,5]diazocines
Author(s) -
Xiao Wang,
Jianzhong Li,
Na Zhao,
Xiaobo Wan
Publication year - 2011
Publication title -
organic letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.94
H-Index - 239
eISSN - 1523-7060
pISSN - 1523-7052
DOI - 10.1021/ol102957c
Subject(s) - chemistry , intermolecular force , combinatorial chemistry , stereochemistry , medicinal chemistry , molecule , organic chemistry
2-Benzoylbenzoyl azides undergo facile cyclization under acidic conditions to give substituted dibenzo[b,f][1,5]-diazocines in good yields. This approach shortens the synthetic steps toward these compounds as compared with conventional methods. The mechanism of the diazocine synthesis is assumed to proceed by an unprecedented intermolecular [2 + 2] cyclization.
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