Open AccessDynamic Ligand Exchange in Reactions of Samarium Diiodide
Author(s) -
Dhandapani V. Sadasivam,
Joseph A. Teprovich,
David J. Procter,
Robert A. Flowers
Publication year - 2010
Publication title -
organic letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.94
H-Index - 239
eISSN - 1523-7060
pISSN - 1523-7052
DOI - 10.1021/ol101722c
Subject(s) - chemistry , samarium diiodide , samarium , iodide , ligand (biochemistry) , substrate (aquarium) , metal , combinatorial chemistry , organic chemistry , biochemistry , oceanography , receptor , geology
Mechanistic studies show the importance of iodide displacement by additives that accelerate reactions of samarium diiodide. The key feature important for acceleration of reaction rate is the use of proton donors and other additives that have a high enough affinity for Sm(II) to displace iodide yet do not saturate the coordination sphere inhibiting substrate reduction.
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